High-throughput 5′P sequencing enables the study of degradation-associated ribosome stalls

Summary: RNA degradation is critical for gene expression and mRNA quality control. mRNA degradation is connected to the translation process up to the degree that 5′-3′ mRNA degradation follows the last translating ribosome. Here, we present an improved high-throughput 5′P degradome RNA-sequencing me...

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Bibliographic Details
Main Authors: Yujie Zhang, Vicent Pelechano
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports: Methods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237521000011