BCMA (TNFRSF17) Induces APRIL and BAFF Mediated Breast Cancer Cell Stemness

BCMA (TNFRSF17) Induces APRIL and BAFF Mediated Breast Cancer Cell Stemness

Recent advances in cancer immunology revealed immune-related properties of cancer cells as novel promising therapeutic targets. The two TNF superfamily members, APRIL (TNFSF13), and BAFF (TNFSF13B), which are type II membrane proteins, released in active forms by proteolytic cleavage and are primari...

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Bibliographic Details
Main Authors: Vasiliki Pelekanou, George Notas, Paraskevi Athanasouli, Konstantinos Alexakis, Fotini Kiagiadaki, Nikolaos Peroulis, Konstantina Kalyvianaki, Errika Kampouri, Hara Polioudaki, Panayiotis Theodoropoulos, Andreas Tsapis, Elias Castanas, Marilena Kampa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Oncology
Subjects:
APRIL (TNFSF13)
BAFF (TNFSF13B)
BCMA (TNFRSF17)
pluripotency
cancer stem cells
therapy resistance
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00301/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00301/full

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