Neonatal Nav1.5 Protein Expression in Human Colorectal Cancer: Immunohistochemical Characterization and Clinical Evaluation

Neonatal Nav1.5 Protein Expression in Human Colorectal Cancer: Immunohistochemical Characterization and Clinical Evaluation

Voltage-gated Na<sup>+</sup> channels (VGSCs) are expressed widely in human carcinomas and play a significant role in promoting cellular invasiveness and metastasis. However, human tissue-based studies and clinical characterization are lacking. In several carcinomas, including colorectal...

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Bibliographic Details
Main Authors: Elena Lastraioli, Scott P. Fraser, R. Mine Guzel, Jessica Iorio, Lapo Bencini, Emanuela Scarpi, Luca Messerini, Vincenzo Villanacci, Giulia Cerino, Niccolo’ Ghezzi, Giuseppe Perrone, Mustafa B. A. Djamgoz, Annarosa Arcangeli
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
colorectal cancer
metastasis
voltage-gated sodium channel
neonatal Nav1.5
immunohistochemistry
Online Access:https://www.mdpi.com/2072-6694/13/15/3832

Internet

https://www.mdpi.com/2072-6694/13/15/3832

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