DYT1 dystonia increases risk taking in humans

It has been difficult to link synaptic modification to overt behavioral changes. Rodent models of DYT1 dystonia, a motor disorder caused by a single gene mutation, demonstrate increased long-term potentiation and decreased long-term depression in corticostriatal synapses. Computationally, such asymm...

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Bibliographic Details
Main Authors: David Arkadir, Angela Radulescu, Deborah Raymond, Naomi Lubarr, Susan B Bressman, Pietro Mazzoni, Yael Niv
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/14155