A Targeted RNAi Screen Reveals Drosophila Female-Sterile Genes That Control the Size of Germline Stem Cell Niche During Development

Adult stem cells maintain tissue homeostasis. This unique capability largely depends on the stem cell niche, a specialized microenvironment, which preserves stem cell identity through physical contacts and secreted factors. In many cancers, latent tumor cell niches are thought to house stem cells an...

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Bibliographic Details
Main Authors: Yueh Cho, Chun-Ming Lai, Kun-Yang Lin, Hwei-Jan Hsu
Format: Article
Language:English
Published: Oxford University Press 2018-07-01
Series:G3: Genes, Genomes, Genetics
Subjects:
GSC
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200355