A Paradigm Revolution or Just Better Resolution—Will Newly Emerging Superresolution Techniques Identify Chromatin Architecture as a Key Factor in Radiation-Induced DNA Damage and Repair Regulation?

DNA double-strand breaks (DSBs) have been recognized as the most serious lesions in irradiated cells. While several biochemical pathways capable of repairing these lesions have been identified, the mechanisms by which cells select a specific pathway for activation at a given DSB site remain poorly u...

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Bibliographic Details
Main Authors: Martin Falk, Michael Hausmann
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/1/18