Comparison of the amniotic fluid and fetal urine peptidome for biomarker discovery in renal developmental disease

Abstract Production of amniotic fluid (AF) is view as predominately driven by excretion of fetal urine (FU). However, the origin of AF peptides, often considered as potential biomarkers of developmental diseases, has never been investigated. Here, we evaluated the FU origin of AF peptides and if the...

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Bibliographic Details
Main Authors: Camille Fédou, Benjamin Breuil, Igor Golovko, Stéphane Decramer, Pedro Magalhães, Françoise Muller, Sophie Dreux, Petra Zürbig, Julie Klein, Joost P. Schanstra, Bénédicte Buffin-Meyer
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78730-3