Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice

Dopamine neurons are thought to encode novelty in addition to reward prediction error (the discrepancy between actual and predicted values). In this study, we compared dopamine activity across the striatum using fiber fluorometry in mice. During classical conditioning, we observed opposite dynamics...

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Bibliographic Details
Main Authors: William Menegas, Benedicte M Babayan, Naoshige Uchida, Mitsuko Watabe-Uchida
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/21886