Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients

Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients

The aim of our study was to set up a panel for targeted sequencing of chemoresistance genes and the main transcription factors driving their expression and to evaluate their predictive and prognostic value in breast cancer patients. Coding and regulatory regions of 509 genes, selected from PharmGKB...

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Bibliographic Details
Main Authors: Viktor Hlavac, Maria Kovacova, Katerina Elsnerova, Veronika Brynychova, Renata Kozevnikovova, Karel Raus, Katerina Kopeckova, Sona Mestakova, David Vrana, Jiri Gatek, Pavel Ostasov, Radka Vaclavikova, Pavel Soucek
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
breast cancer
chemoresistance
pharmacogenomics
next generation sequencing
in silico prediction
Online Access:https://www.mdpi.com/2072-6694/10/12/511

Internet

https://www.mdpi.com/2072-6694/10/12/511

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