Daily corticosterone rhythm modulates pineal function through NFκB-related gene transcriptional program

Abstract Melatonin and glucocorticoids are key hormones in determining daily rhythmicity and modulating defense responses. In nocturnal animals, corticosterone peaks at light/dark transition,while melatonin peaks at the middle of the night in both nocturnal and diurnal animals. The crosstalk between...

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Bibliographic Details
Main Authors: Sanseray da Silveira Cruz-Machado, Eduardo K. Tamura, Claudia E. Carvalho-Sousa, Vanderlei Amadeu Rocha, Luciana Pinato, Pedro A. C. Fernandes, Regina P. Markus
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02286-y