Alkaloids from Nelumbinis Plumula (AFNP) ameliorate aortic remodeling via RhoA/ROCK pathway

Alkaloids from Nelumbinis Plumula (AFNP) ameliorate aortic remodeling via RhoA/ROCK pathway

The protective role of alkaloids from Nelumbinis Plumula (AFNP) on the aorta during hypertension is not yet fully understood. We hypothesize that AFNP exerts protective effects against Ang II-induced hypertension by mediating RhoA/ROCK pathway and phenotypic switching during hypertension. In the pre...

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Bibliographic Details
Main Authors: Qiongyu Li, Da Wo, Yue Huang, Na Yu, Jianwei Zeng, Hongwei Chen, Huai Wang, Liya Bao, Shan Lin, JianFeng Chu, Jun Peng
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Hypertension
Vascular remodeling
Smooth muscle
Phenotypic switching
RhoA/ROCK pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218381204

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218381204

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