Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes

<p>Abstract</p> <p>Background</p> <p>The animal sialyltransferases, which catalyze the transfer of sialic acid to the glycan moiety of glycoconjugates, are subdivided into four families: ST3Gal, ST6Gal, ST6GalNAc and ST8Sia, based on acceptor sugar specificity and glyco...

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Bibliographic Details
Main Authors: Petit Jean-Michel, Delannoy Philippe, Mollicone Rosella, Petit Daniel, Harduin-Lepers Anne, Oriol Rafael
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/8/258