Omega-3 fatty acid ethyl-eicosapentaenoate, but not soybean oil, attenuates memory impairment induced by central IL-1β administration

Proinflammatory cytokine interleukin (IL)-1β can cause cognitive impairment, activate the hypothalamic-pituitary-adrenal axis and impair monoaminergic neurotransmission in the rat. IL-1β has also been shown to increase the concentration of the inflammatory mediator prostaglandin E2 (PGE2) in the blo...

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Bibliographic Details
Main Authors: Cai Song, David Horrobin
Format: Article
Language:English
Published: Elsevier 2004-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318095