Characterisation of Lamp2-deficient rats for potential new animal model of Danon disease

Characterisation of Lamp2-deficient rats for potential new animal model of Danon disease

Abstract Danon disease (DD) is caused by the absence or malfunction of lysosomal-associated membrane protein 2 (LAMP2). Although Lamp2-deficient mice and DD patients have similar characteristics, these mice have clear limitations and are clinically inconsistent. The aim of our paper is to outline th...

Full description

Bibliographic Details
Main Authors: Shuoyi Ma, Miao Zhang, Shuai Zhang, Jing Wang, Xia Zhou, Guanya Guo, Lu Wang, Min Wang, Zhengwu Peng, Changcun Guo, Xiaohong Zheng, Xinmin Zhou, Jingbo Wang, Ying Han
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-24351-w

Internet

https://doi.org/10.1038/s41598-018-24351-w

Similar Items