5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice

<p>Abstract</p> <p>Background</p> <p>The role of serotonin (5-hydroxytrptamine, 5-HT) in the modulation of pain has been widely studied. Previous work led to the hypothesis that 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, might by itself influenc...

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Bibliographic Details
Main Authors: Moessner Rainald, Gerlach Manfred, Lesch Klaus-Peter, Palm Florian, Chen Yong, Sommer Claudia
Format: Article
Language:English
Published: SAGE Publishing 2011-03-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/7/1/21