Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

Mucoadhesive nanostructured systems comprising poloxamer 407 and Carbopol 974P® have already demonstrated good mucoadhesion, as well as improved mechanical and rheological properties. Curcumin displays excellent biological activity, mainly in oral squamous cancer; however, its physicochemical charac...

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Bibliographic Details
Main Authors: Sabrina Barbosa de Souza Ferreira, Gustavo Braga, Évelin Lemos Oliveira, Jéssica Bassi da Silva, Hélen Cássia Rosseto, Lidiane Vizioli de Castro Hoshino, Mauro Luciano Baesso, Wilker Caetano, Craig Murdoch, Helen Elizabeth Colley, Marcos Luciano Bruschi
Format: Article
Language:English
Published: Beilstein-Institut 2019-11-01
Series:Beilstein Journal of Nanotechnology
Subjects:
curcumin
mucoadhesion
oral squamous cell carcinoma
permeation
poloxamer 407
Online Access:https://doi.org/10.3762/bjnano.10.222

Internet

https://doi.org/10.3762/bjnano.10.222

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