Epigallocatechin-3-Gallate Induces Apoptosis as a TRAIL Sensitizer via Activation of Caspase 8 and Death Receptor 5 in Human Colon Cancer Cells

Though epigallocatechin-3-gallate (EGCG), a major compound of green tea, has anti-diabetes, anti-obesity, anti-inflammatory, and antitumor effects, the underlying antitumor molecular mechanism of EGCG was not fully understood so far. Here the sensitizing effect of EGCG to tumor-necrosis-factor-relat...

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Bibliographic Details
Main Authors: Oh Sung Kwon, Ji Hoon Jung, Eun Ah Shin, Ji Eon Park, Woon Yi Park, Sung-Hoon Kim
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomedicines
Subjects:
DR5
Online Access:https://www.mdpi.com/2227-9059/8/4/84