Evolution of the bovine TLR gene family and member associations with Mycobacterium avium subspecies paratuberculosis infection.

Members of the Toll-like receptor (TLR) gene family occupy key roles in the mammalian innate immune system by functioning as sentries for the detection of invading pathogens, thereafter provoking host innate immune responses. We utilized a custom next-generation sequencing approach and allele-specif...

Full description

Bibliographic Details
Main Authors: Colleen A Fisher, Eric K Bhattarai, Jason B Osterstock, Scot E Dowd, Paul M Seabury, Meenu Vikram, Robert H Whitlock, Ynte H Schukken, Robert D Schnabel, Jeremy F Taylor, James E Womack, Christopher M Seabury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3227585?pdf=render