Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells

Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells

Chromosomal aneuploidy is a defining feature of epithelial cancers. The pattern of aneuploidies is cancer-type specific. For instance, the gain of chromosome 13 occurs almost exclusively in colorectal cancer. We used microcell-mediated chromosome transfer to generate gains of chromosome 13 in the di...

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Bibliographic Details
Main Authors: Darawalee Wangsa, Rüdiger Braun, Christina H. Stuelten, Markus Brown, Kerry M. Bauer, Georg Emons, Leigh A. Weston, Yue Hu, Howard H. Yang, Maria Vila-Casadesús, Maxwell P. Lee, Philip Brauer, Lidia Warner, Madhvi Upender, Amanda B. Hummon, Jordi Camps, Thomas Ried
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619301289

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http://www.sciencedirect.com/science/article/pii/S1476558619301289

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