Maternal Inflammation Contributes to Brain Overgrowth and Autism-Associated Behaviors through Altered Redox Signaling in Stem and Progenitor Cells

Maternal Inflammation Contributes to Brain Overgrowth and Autism-Associated Behaviors through Altered Redox Signaling in Stem and Progenitor Cells

A period of mild brain overgrowth with an unknown etiology has been identified as one of the most common phenotypes in autism. Here, we test the hypothesis that maternal inflammation during critical periods of embryonic development can cause brain overgrowth and autism-associated behaviors as a resu...

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Bibliographic Details
Main Authors: Janel E. Le Belle, Jantzen Sperry, Amy Ngo, Yasmin Ghochani, Dan R. Laks, Manuel López-Aranda, Alcino J. Silva, Harley I. Kornblum
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114002896

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http://www.sciencedirect.com/science/article/pii/S2213671114002896

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