High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA

The binding specificity of botulinum neurotoxins (BoNTs) is primarily a consequence of their ability to bind to multiple receptors at the same time. BoNTs consist of three distinct domains, a metalloprotease light chain (LC), a translocation domain (HN) and a receptor-binding domain (HC). Here we re...

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Bibliographic Details
Main Authors: Jonathan R. Davies, Gavin S. Hackett, Sai Man Liu, K. Ravi Acharya
Format: Article
Language:English
Published: PeerJ Inc. 2018-03-01
Series:PeerJ
Subjects:
SV2
Online Access:https://peerj.com/articles/4552.pdf