Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series

Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series

Background: There is increasing concern that persistent infection of SARS-CoV-2 within immunocompromised hosts could serve as a reservoir for mutation accumulation and subsequent emergence of novel strains with the potential to evade immune responses. Methods: We describe three patients with acute l...

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Bibliographic Details
Main Authors: Thao T. Truong, Alex Ryutov, Utsav Pandey, Rebecca Yee, Lior Goldberg, Deepa Bhojwani, Paibel Aguayo-Hiraldo, Benjamin A. Pinsky, Andrew Pekosz, Lishuang Shen, Scott D. Boyd, Oliver F. Wirz, Katharina Röltgen, Moiz Bootwalla, Dennis T. Maglinte, Dejerianne Ostrow, David Ruble, Jennifer H. Han, Jaclyn A. Biegel, Maggie Li, ChunHong Huang, Malaya K. Sahoo, Pia S. Pannaraj, Maurice O'Gorman, Alexander R. Judkins, Xiaowu Gai, Jennifer Dien Bard
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:EBioMedicine
Subjects:
SARS-CoV-2
immunocompromised
persistent infection
variants
case report
pediatric
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421001481

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http://www.sciencedirect.com/science/article/pii/S2352396421001481

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