Lipopolysaccharide-Induced Systemic Inflammation in the Neonatal Period Increases Microglial Density and Oxidative Stress in the Cerebellum of Adult Rats

Lipopolysaccharide-Induced Systemic Inflammation in the Neonatal Period Increases Microglial Density and Oxidative Stress in the Cerebellum of Adult Rats

Inflammatory processes occurring in the perinatal period may affect different brain regions, resulting in neurologic sequelae. Injection of lipopolysaccharide (LPS) at different neurodevelopmental stages produces long-term consequences in several brain structures, but there is scarce evidence regard...

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Bibliographic Details
Main Authors: Jaime Moreira Pires, Maira Licia Foresti, Clivandir Severino Silva, Débora Bandeira Rêgo, Michele Longoni Calió, Amanda Cristina Mosini, Thabatta Karollynne Estevam Nakamura, Ana Teresa F. Leslie, Luiz Eugênio Mello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
lipopolysaccharide
neuroinflammation
Purkinje cell
oxidative stress
neonatal
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00142/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00142/full

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