Role of AMPK and Akt in triple negative breast cancer lung colonization

Triple negative breast cancer (TNBC) is an aggressive disease with a 5-y relative survival rate of 11% after distant metastasis. To survive the metastatic cascade, tumor cells remodel their signaling pathways by regulating energy production and upregulating survival pathways. AMP-activated protein k...

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Bibliographic Details
Main Authors: Jeremy Johnson, Zeta Chow, Eun Lee, Heidi L. Weiss, B. Mark Evers, Piotr Rychahou
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558621000154