Mepolizumab in the management of severe eosinophilic asthma in adults: current evidence and practical experience
Eosinophils represent approximately 1% of peripheral blood leukocytes in normal donors and their maturation and differentiation in the bone marrow are mainly regulated by interleukin (IL)-5 [Broughton et al. 2015]. IL-5, a cytokine that belongs to the β common-chain family, together with IL-3 and gr...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-01-01
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Series: | Therapeutic Advances in Respiratory Disease |
Online Access: | https://doi.org/10.1177/1753465816673303 |