Uric acid level has a U-shaped association with loss of kidney function in healthy people: a prospective cohort study.

BACKGROUND:The relationship between hyperuricemia and chronic kidney disease (CKD) has been found in various observational studies. Although hypouricemia is associated with cardiovascular events, it has not been established as a risk factor for CKD. We investigated the relationship between serum uri...

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Bibliographic Details
Main Authors: Eiichiro Kanda, Toshitaka Muneyuki, Yoshihiko Kanno, Kaname Suwa, Kei Nakajima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4320097?pdf=render