Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma
Despite intensive multimodal therapy, the survival rate for high risk neuroblastoma (HR-NB) remains <50%. Most cases initially respond to treatment but almost half will subsequently relapse with aggressive treatment resistant disease. Novel treatments exploiting the molecular pathology of NB...
Main Authors: | Harriet E. D. Southgate, Lindi Chen, Nicola J. Curtin, Deborah A. Tweddle |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-04-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2020.00371/full |
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