Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein.

Infections with emerging and re-emerging arboviruses are of increasing concern for global health. Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as indicated by the recent emergence of Bourbon virus in the USA. To successfu...

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Bibliographic Details
Main Authors: Jonas Fuchs, Alexander Oschwald, Laura Graf, Georg Kochs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009038