Synthesis and Evaluation of Spumigin Analogues Library with Thrombin Inhibitory Activity
Spumigins are marine natural products derived from cyanobacteria <i>Nodularia spumigena</i>, which mimics the structure of the <span style="font-variant: small-caps;">d</span>-Phe-Pro-Arg sequence and is crucial for binding to the active site of serine proteases thr...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
|
Series: | Marine Drugs |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-3397/16/11/413 |