Synthesis and Evaluation of Spumigin Analogues Library with Thrombin Inhibitory Activity

Spumigins are marine natural products derived from cyanobacteria <i>Nodularia spumigena</i>, which mimics the structure of the <span style="font-variant: small-caps;">d</span>-Phe-Pro-Arg sequence and is crucial for binding to the active site of serine proteases thr...

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Bibliographic Details
Main Authors: Aleš Žula, Izabela Będziak, Danijel Kikelj, Janez Ilaš
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/16/11/413