Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels

Disruption of the murine procollagen C-proteinase enhancer 2 gene causes accumulation of pro-apoA-I and increased HDL levels

Given the increased prevalence of cardiovascular disease in the world, the search for genetic variations that impact risk factors associated with the development of this disease continues. Multiple genetic association studies demonstrate that procollagen C-proteinase enhancer 2 (PCPE2) modulates HDL...

Full description

Bibliographic Details
Main Authors: Omar L. Francone, Brian Y. Ishida, Margarita de la Llera-Moya, Lori Royer, Christiane Happe, Jian Zhu, Robert J. Chalkey, Peter Schaefer, Cheryl Cox, Al Burlingame, John P. Kane, George H. Rothblat
Format: Article
Language:English
Published: Elsevier 2011-11-01
Series:Journal of Lipid Research
Subjects:
apolipoprotein A-I synthesis
PCPE2
high density lipoprotein metabolism
cholesterol efflux
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520350872

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520350872

Similar Items