A Possible Mechanism of Metformin in Improving Insulin Resistance in Diabetic Rat Models

Background. Type 2 diabetes has become one of the most common diseases worldwide, causing a serious social burden. As a first-line treatment for diabetes, metformin can effectively improve insulin resistance. It has been reported that 12α-hydroxylated BA (mainly CA) is associated with insulin resist...

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Bibliographic Details
Main Authors: Mengsiyu Li, Xiaowen Hu, Yeqiu Xu, Xiaolin Hu, Chunxue Zhang, Shuguang Pang
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2019/3248527