The JAK2 GGCC (46/1) Haplotype in Myeloproliferative Neoplasms: Causal or Random?

The JAK2 GGCC (46/1) Haplotype in Myeloproliferative Neoplasms: Causal or Random?

The germline JAK2 haplotype known as “GGCC or 46/1 haplotype” (haplotypeGGCC_46/1) consists of a combination of single nucleotide polymorphisms (SNPs) mapping in a region of about 250 kb, extending from the JAK2 intron 10 to the Insulin-like 4 (INLS4) gene. Four main SNPs (rs3780367, rs10974944, rs1...

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Bibliographic Details
Main Authors: Luisa Anelli, Antonella Zagaria, Giorgina Specchia, Francesco Albano
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
JAK2 germline haplotype
single nucleotide polymorphisms
myeloproliferative neoplasms
Online Access:http://www.mdpi.com/1422-0067/19/4/1152

Internet

http://www.mdpi.com/1422-0067/19/4/1152

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