A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens
Abstract Background Tuberculosis kills more people than any other infectious disease, and new regimens are essential. The primary endpoint for confirmatory phase III trials for new regimens is a composite outcome that includes bacteriological treatment failure and relapse. Culture methodology is cri...
Main Authors: | Patrick P. J. Phillips, Carl M. Mendel, Andrew J. Nunn, Timothy D. McHugh, Angela M. Crook, Robert Hunt, Anna Bateson, Stephen H. Gillespie |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | BMC Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12916-017-0955-9 |
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