A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens

A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens

Abstract Background Tuberculosis kills more people than any other infectious disease, and new regimens are essential. The primary endpoint for confirmatory phase III trials for new regimens is a composite outcome that includes bacteriological treatment failure and relapse. Culture methodology is cri...

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Bibliographic Details
Main Authors: Patrick P. J. Phillips, Carl M. Mendel, Andrew J. Nunn, Timothy D. McHugh, Angela M. Crook, Robert Hunt, Anna Bateson, Stephen H. Gillespie
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Medicine
Subjects:
Tuberculosis
MGIT
LJ
Clinical trials
Relapse
Culture media
Online Access:http://link.springer.com/article/10.1186/s12916-017-0955-9

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http://link.springer.com/article/10.1186/s12916-017-0955-9

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