Decreased CD8+ Lymphocytic Infiltration in Multifocal and Multicentric Glioblastomas

Decreased CD8+ Lymphocytic Infiltration in Multifocal and Multicentric Glioblastomas

PurposeMultifocal and multicentric glioblastomas (mGBMs) are associated with a poorer prognosis compared to unifocal glioblastoma (uGBM). The presence of CD8+ tumor-infiltrating lymphocytes (TILs) is predictive of clinical outcomes in human malignancies. Here, we examined the CD8+ lymphocytic infilt...

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Bibliographic Details
Main Authors: Run Wang, Yifu Song, Tianhao Hu, Xiaoliang Wang, Yang Jiang, Di Zhang, Juanhan Yu, Sheng Han, Liang Kan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
Multifocal glioma
CD8
tumor-infiltrating lymphocytes (TILs)
chemotherapy
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.748277/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.748277/full

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