RANK Deficiency Ameliorates Podocyte Injury by Suppressing Calcium/Calcineurin/ NFATc1 Signaling

RANK Deficiency Ameliorates Podocyte Injury by Suppressing Calcium/Calcineurin/ NFATc1 Signaling

Background/Aims: Podocyte injury and loss contribute to proteinuria, glomerulosclerosis and eventually kidney failure. Receptor activator of NF-κB (RANK) belongs to the TNF receptor superfamily, which plays a key role in the pathogenesis of podocyte injury. However, the mechanism underlying the effe...

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Bibliographic Details
Main Authors: Shun Liang, Hong Zhang, Yue Du, Caoshuai Dou, Shuangxin Liu, Li Zhang, Yuanhan Chen, Ruizhao Li, Jianchao Ma, Zhuo Li, Ting Lin, Xinchen Zhao, Qianmei Zhang, Wenjian Wang, Zhiming Ye, Xinling Liang, Wei Shi, Bin Zhang
Format: Article
Language:English
Published: Karger Publishers 2018-07-01
Series:Kidney & Blood Pressure Research
Subjects:
Podocyte
Injury
Receptor activator of NF-κB
Nuclear factor of activated T cells
Online Access:https://www.karger.com/Article/FullText/492049

Internet

https://www.karger.com/Article/FullText/492049

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