Elevated androstenedione in young adult but not early adolescent prenatally androgenized female rats.

Elevated testosterone (T) is routinely reported as a marker of hyperandrogenemia in rodent models for polycystic ovary syndrome (PCOS). In women with PCOS, elevated serum androstenedione (A4) is associated with more severe phenotypes, including a positive correlation with serum T, DHEAS, free androg...

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Bibliographic Details
Main Authors: Ami B Shah, Isaac Nivar, Diana L Speelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5933698?pdf=render