Characterisation of the Myocardial Mitochondria Structural and Functional Phenotype in a Murine Model of Diabetic Cardiomyopathy

Characterisation of the Myocardial Mitochondria Structural and Functional Phenotype in a Murine Model of Diabetic Cardiomyopathy

People affected by diabetes are at an increased risk of developing heart failure than their non-diabetic counterparts, attributed in part to a distinct cardiac pathology termed diabetic cardiomyopathy. Mitochondrial dysfunction and excess reactive oxygen species (ROS) have been implicated in a range...

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Bibliographic Details
Main Authors: Alex M. Parker, Mitchel Tate, Darnel Prakoso, Minh Deo, Andrew M. Willis, David M. Nash, Daniel G. Donner, Simon Crawford, Helen Kiriazis, Cesare Granata, Melinda T. Coughlan, Miles J. De Blasio, Rebecca H. Ritchie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
diabetes
heart
experimental – animal models
mitochondria
diabetic cardiomyopathy
mitochondrial function
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.672252/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.672252/full

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