The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth

The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth

Although some studies suggested that disruption of the Hippo signaling pathway is associated with osteosarcoma progression, the molecular mechanisms by which YAP regulates primary tumor growth is not fully clarified. In addition, the validation of YAP as a therapeutic target through the use of inhib...

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Bibliographic Details
Main Authors: Sarah Morice, Mathilde Mullard, Regis Brion, Maryne Dupuy, Sarah Renault, Robel Tesfaye, Bénédicte Brounais-Le Royer, Benjamin Ory, Françoise Redini, Franck Verrecchia
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
osteosarcoma
Hippo/YAP
tumor growth
Verteporfin
CA3
Online Access:https://www.mdpi.com/2072-6694/12/12/3847

Internet

https://www.mdpi.com/2072-6694/12/12/3847

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