Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner

Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner

Abstract Background The non-structural protein 1 (NS1) of influenza A virus (IAV) is a key player in inhibiting antiviral response in host cells, thereby facilitating its replication. However, other roles of NS1, which are independent of antagonising host cells’ antiviral response, are less characte...

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Bibliographic Details
Main Authors: Tim Wai Sha, Michaela Weber, Dacquin M. Kasumba, Takeshi Noda, Masahiro Nakano, Hiroki Kato, Takashi Fujita
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Virology Journal
Subjects:
Influenza a virus
Non-structural protein 1
Innate immunity
Genome packaging
Virus-like production system
dsRNA binding domain
Online Access:http://link.springer.com/article/10.1186/s12985-020-01357-3

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http://link.springer.com/article/10.1186/s12985-020-01357-3

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