Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes

Summary: Energy metabolism is a key aspect of cardiomyocyte biology. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a promising tool for biomedical application, but they are immature and have not undergone metabolic maturation related to early postnatal development. To as...

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Bibliographic Details
Main Authors: Bärbel M. Ulmer, Andrea Stoehr, Mirja L. Schulze, Sajni Patel, Marjan Gucek, Ingra Mannhardt, Sandra Funcke, Elizabeth Murphy, Thomas Eschenhagen, Arne Hansen
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118300651