Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate

Our understanding of how the germline of the parasitic flatworm Schistosoma mansoni develops is limited. Here, the authors use single cell RNAseq and functional genomic analysis of juvenile worms to identify a regulatory program that mediates the fate of germline stem cells between proliferation and...

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Bibliographic Details
Main Authors: Pengyang Li, Dania Nanes Sarfati, Yuan Xue, Xi Yu, Alexander J. Tarashansky, Stephen R. Quake, Bo Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20794-w