Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells

Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells

Of the thousands of long noncoding RNAs expressed in embryonic stem cells (ESCs), few have known roles and fewer have been functionally implicated in the regulation of self-renewal and pluripotency, or the reprogramming of somatic cells to the pluripotent state. In ESCs, Cyrano is a stably expressed...

Full description

Bibliographic Details
Main Authors: Keriayn N. Smith, Joshua Starmer, Sarah C. Miller, Praveen Sethupathy, Terry Magnuson
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Stem Cell Reports
Subjects:
Cyrano
lncRNA
embryonic stem cells
self-renewal
cell survival
mir-7
nanog
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117302126

Internet

http://www.sciencedirect.com/science/article/pii/S2213671117302126

Similar Items