Increased SPARC expression is associated with neoadjuvant therapy in resectable pancreatic ductal adenocarcinoma

Increased SPARC expression is associated with neoadjuvant therapy in resectable pancreatic ductal adenocarcinoma

Secreted Protein Acid and Rich in Cysteine (SPARC) is an extracellular glycoprotein secreted by fibroblasts and osteoblasts in normal tissues. SPARC overexpression occurs in multiple tumors including pancreatic ductal adenocarcinoma (PDAC) and may predict favorable response to nab-paclitaxel. The pr...

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Bibliographic Details
Main Authors: Christopher Hartley, Daniel Rowan, Xiuxu Chen, Luisa Gomez-Arellano, Anna Marie West, Kiyoko Oshima, Alexander Craig Mackinnon
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Practical Laboratory Medicine
Subjects:
SPARC
Pancreatic cancer
Neoadjuvant therapy
Adjuvant therapy
Immunohistochemistry
Digital image analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551719301015

Internet

http://www.sciencedirect.com/science/article/pii/S2352551719301015

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