Biological impact of the TSH-beta splice variant in health and disease

Biological impact of the TSH-beta splice variant in health and disease

Thyroid stimulating hormone (TSH), a glycoprotein hormone composed of alpha and beta chains, is produced by thryrotrope cells of the anterior pituitary. Within the conventional endocrine loop, pituitary-derived TSH binds to receptors in the thyroid, resulting in the release of the thyroid hormones...

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Bibliographic Details
Main Author: John R. Klein
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Immunology
Subjects:
Bone Marrow
thyroid
hormone
Pituitary
isoform
alternatively-spliced
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00155/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00155/full

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