Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss

Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss

Volumetric muscle loss (VML) injuries after extremity trauma results in an important clinical challenge often associated with impaired healing, significant fibrosis, and long-term pain and functional deficits. While acute muscle injuries typically display a remarkable capacity for regeneration, crit...

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Bibliographic Details
Main Authors: Cheryl L. San Emeterio, Lauren A. Hymel, Thomas C. Turner, Molly E. Ogle, Emily G. Pendleton, William Y. York, Claire E. Olingy, Alan Y. Liu, Hong Seo Lim, Todd A. Sulchek, Gordon L. Warren, Luke J. Mortensen, Peng Qiu, Young C. Jang, Nick J. Willett, Edward A. Botchwey
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
immunomodulation
inflammation
tissue engineering
regeneration
sphingolipid
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.650289/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.650289/full

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