A unified conformational selection and induced fit approach to protein-peptide docking.

Protein-peptide interactions are vital for the cell. They mediate, inhibit or serve as structural components in nearly 40% of all macromolecular interactions, and are often associated with diseases, making them interesting leads for protein drug design. In recent years, large-scale technologies have...

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Bibliographic Details
Main Authors: Mikael Trellet, Adrien S J Melquiond, Alexandre M J J Bonvin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23516555/?tool=EBI