The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function.

Clostridium difficile is the main cause of antibiotic-associated diarrhea, leading to significant morbidity and mortality and putting considerable economic pressure on healthcare systems. Current knowledge of the molecular basis of pathogenesis is limited primarily to the activities and regulation o...

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Bibliographic Details
Main Authors: Catherine B Reynolds, Jenny E Emerson, Lucia de la Riva, Robert P Fagan, Neil F Fairweather
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3080850?pdf=render