Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes

The use of stem cell-derived cardiomyocytes for heart repair is hampered by their immature structural and contractile properties that may cause arrhythmia. Here, Eng et al.show that electrical conditioning of human cardiomyocytes in 3D culture can enhance connectivity and provide resistance to arrhy...

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Bibliographic Details
Main Authors: George Eng, Benjamin W. Lee, Lev Protas, Mark Gagliardi, Kristy Brown, Robert S. Kass, Gordon Keller, Richard B. Robinson, Gordana Vunjak-Novakovic
Format: Article
Language:English
Published: Nature Publishing Group 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10312