A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I

A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I

Glycosylation, a common modification of cellular proteins and lipids, is often altered in diseases and pathophysiological states such as hypoxia, yet the underlying molecular causes remain poorly understood. By utilizing lectin microarray glycan profiling, Golgi pH and redox screens, we show here th...

Full description

Bibliographic Details
Main Authors: Antti Hassinen, Fawzi Khoder-Agha, Elham Khosrowabadi, Daniela Mennerich, Deborah Harrus, Maxence Noel, Elitsa Y. Dimova, Tuomo Glumoff, Anne Harduin-Lepers, Thomas Kietzmann, Sakari Kellokumpu
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719301983

Internet

http://www.sciencedirect.com/science/article/pii/S2213231719301983

Similar Items